□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□ □ □ □ □□□ □ □□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□ □ □ □□□□□□□□□□□□□□□□□□ □ □□□ □□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□□Professor Associate Professor Assistant Professor Specially Appointed Professor Specially Appointed Professor Hiroaki SASAI Specially Appointed Professor Kazushi MASHIMA Specially Appointed Senior Assistant Professor Koji MORIMOTO Mitsuhiro ARISAWA Atsushi Nakayama Makoto SAKO Jun-ichi UENISHI Fax 06-6879-8226, 82271）有機合成化学を基盤とするライフサイエンスへのアプローチ2）機能性分子（生物活性化合物・イメージング色素など）の設計・合成・評価3）環境調和型化学（グリーンケミストリー）の開拓4）元素（遷移金属・典型金属・半金属・非金属）や官能基の特性を生かした新反応の開発5）多置換・多環性ヘテロ環の設計・合成arisaw@phs.osaka-u.ac.jp 06-6879-8226 06-6879-8227 anakayama@phs.osaka-u.ac.jpsako-m@phs.osaka-u.ac.jp06-6879-8228 juenishi@phs.osaka-u.ac.jp06-6879-8228 06-6879-8228 sasai@sanken.osaka-u.ac.jp06-6879-8229 mashima@phs.osaka-u.ac.jpmorimoto@phs.osaka-u.ac.jp06-6879-8228 教 授 有澤光弘 准教授 中山 淳 助 教 佐古 真 特任教授 上西潤一 特任教授 笹井宏明 特任教授 真島和志 特任講師 森本功治 教授 有澤 光弘1. Arisawa M., et al., Design and Synthesis of 4-Acetoxypentanamide Derivatives of Spliceostatin A and Their Biological Evaluation towards Prostate Cancer Treatment. Bioorg. Med. Chem. Lett., 91, 129333 (2023).2. Arisawa M., et al., Reagent-Controlled Regioselective Intramolecular [2+2] Cycloaddition between Vinylsilanes and Allenes, Chem. Eur. J., 29, e202203556 (2023).3. Arisawa M., et al., Development of Cycloisomerization with Rearrangement of a Tosyl Group Using N-Tosyl-o-allenylaniline. J. Org. Chem, 88, 11268 (2023).4. Arisawa M., et al., Design, Synthesis, and Monoamine Oxidase B Selective Inhibitory Activity of N-Arylated Heliamine Analogues. ACS Med. Chem. Lett., 13, 1582–1590 (2022).5. Nakayama A., et al., Total Synthesis of Bipenicilisorin and Assignment of the Absolute Configuration. J. Nat. Prod., 87, 1394–1400 (2024).6. Nakayama A., Studies on Comprehensive Total Synthesis of Natural and Pseudo-Natural Products for Drug Discovery. Chem. Pharm. Bull., 72, 422–431 (2024).7. Sako M., et al., Brønsted acid-catalyzed synthesis of spirocyclobutanes via heteroannulation of vinyloxyphenylbicyclobutanes with water. Org. Biomol. Chem., 22, 4727–4731 (2024).8. Sako M., et al., Axially Chiral Borinic Acid Catalysts: Design, Synthesis, and Application in Alkylative Desymmetrization of 1,2-Diols. J. Org. Chem., 88, 14178–14183 (2023).□□□□□□□□Synthetic Organic Chemistry for Drug Development
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